Prevalence of Hepatitis B virus, Hepatitis C virus and HIV in blood donors of different areas of Khyber Pukhtoonkhwa, Pakistan

Paper Details

Research Paper 01/07/2016
Views (226) Download (6)
current_issue_feature_image
publication_file

Prevalence of Hepatitis B virus, Hepatitis C virus and HIV in blood donors of different areas of Khyber Pukhtoonkhwa, Pakistan

Tariq Ahmed, Rahool, Noor Nasir Khattak, Faizullah Khan, Shahabudddin, Muhammad Saleem Khan
J. Bio. Env. Sci.9( 1), 304-309, July 2016.
Certificate: JBES 2016 [Generate Certificate]

Abstract

It is common to donate blood to save lives of critical patients the carefully transfusion of blood and screening of blood donors is essential to test the blood for the purpose to stop the spreading of the infectious agents trough blood components. Hepatitis is one of the major cause of all the deaths throughout the world as in present, record of past and feature the diseases has alarming signals. The retrospective study period of one year was conducted to show the prevalence of HBV and HCV along with HIV in the blood donors of KPK, Pakistan the information will be helpful for general population which had been remained aware less and unwarned. In current study 8439 blood donors’ data were examined from well-known blood bank of KPK. The 98.9% donors were HBV negative and 1.1% positive. The 99.3% donors were HCV negative and 0.5% positiv e. Overall prevalence of the hepatitis virus (both B and C) was low in the blood donors. The prevalence of HIV is negligible with only one sample found positive. It is concluded that, HBV, HCV and HIV transmission and occurrence low comparative to other province due to awareness, preventive measures and vaccines availability in the KPK.

VIEWS 3

Ali M, Idrees M, Ali L, Hussain A, Rehman IU, Saleem S, Afzal S, Butt S. 2011. Hepatitis B virus in Pakistan: a systematic review of prevalence, risk factors, awareness status and genotypes. Virology journal 8(1), 1.

Batool A, Bano K, Hussain R. 2008. Antenatal screening of women for hepatitis B and C in an out-patient department. Journal of the Dow University of Health Sciences 2(1), 32-35.

Bernal W, Wendon J. 2013. Acute liver failure. New England Journal of Medicine 369(26), 2525-2534.

Brown LD, Ashman D. 1996. Participation, social capital, and intersectoral problem solving: African and Asian cases. World development 24(9), 1467-1479.

Choudhary I, Khan S. 2005. Samiullah. Should we do Hepatitis-B and C screening on each patient before surgery. Pak J Med Sci 21(3), 278-280.

Ganem D, Schneider RJ. 2001. Hepadnaviridae: the viruses and their replication. Fields virology 2, 2923-2969.

Hussain A, Mumtaz H, Aslam M, Abbas Z. 2015. Seroprevalence of transfusion based transmissible infections among clinically healthy donors in the community of Multan. Pakistan. J. Inf. Mol. Biol 3(2), 47-51.

Ilyas M, Iftikhar M, Rasheed U. 2011. Prevalence of hepatitis B and hepatitis C in populations of college students in Gujranwala. Biologia (Pakistan) 57, 89-95.

Khan A, Tareen AM, Ikram A, Rahman H, Wadood A, Qasim M, Khan K. 2013. Prevalence of HCV among the young male blood donors of Quetta region of Balochistan, Pakistan. Virology journal 10(1), 1.

Khan E, Hasan R, Mehraj V, Nasir A, Siddiqui J, Hewson R. 2008. Co-circulations of two genotypes of dengue virus in 2006 out-break of dengue hemorrhagic fever in Karachi, Pakistan. Journal of Clinical Virology 43(2), 176-179.

Khan MA, Islam S, Arif M. 2013. Transmission model of hepatitis b virus with the migration effect. BioMed research international 2013.

Khanani RM, Hafeez A, Rab S, Rasheed S. 1988. Human immunodeficiency virus-associated disorders in Pakistan. AIDS research and human retroviruses 4(2), 149-154.

Khattak M, Salamat N, Bhatti F, Qureshi T. 2002. Seroprevalence of hepatitis B, C and HIV in blood donors in northern Pakistan. J Pak Med Assoc 52(9), 398-402.

Li HM, Wang JQ, Wang R, Zhao Q, Li L, Zhang JP, Shen T. 2015. Hepatitis B virus genotypes and genome characteristics in China. World J Gastroenterol 21(21), 6684-6697.

Malik A, Butt S, Tariq W. 1996. Hepatitis C virus in perspective, where do we stand [editorial]. J Coll Physician Surg Pak 6, 136.

Malik I, Legters L, Luqman M, Ahmed A, Qamar M, Akhtar K, Quraishi M, Duncan F, Redfield R. 1988. The serological markers of hepatitis A and B in healthy population in northern Pakistan. JPMA. The Journal of the Pakistan Medical Association 38(3), 69.

Masood Z, Jawaid M, Khan RA, Rehman S. 2005. Screening for hepatitis B & C: a routine pre-operative investigation. Pakistan Journal of Medical Sciences 21(4), 455.

Muzaffar F, Hussain I, Haroon TS. 2008. Hepatitis C: the dermatologic profile. J Pak Assoc Dermatol 18, 171-181.

Nathans R, Chu C-y, Serquina AK, Lu CC, Cao H, Rana TM. 2009. Cellular microRNA and P bodies modulate host-HIV-1 interactions. Molecular cell 34(6), 696-709.

Rai MA, Warraich HJ, Ali SH, Nerurkar VR. 2007. HIV/AIDS in Pakistan: the battle begins. Retrovirology 4(1), 22.

Re VL, Kostman J. 2005. Management of chronic hepatitis C. Postgraduate medical journal 81(956), 376-382.

Shah SA, Altaf A, Mujeeb SA, Memon A. 2004. An outbreak of HIV infection among injection drug users in a small town in Pakistan: potential for national implications. International Journal of STD and AIDS 15(3), 209.

Sharma SD. 2010. Hepatitis C virus: molecular biology & current therapeutic options.

Sultan F, Mehmood T, Mahmood MT. 2007. Infectious pathogens in volunteer and replacement blood donors in Pakistan: a ten-year experience. International journal of infectious diseases 11(5), 407-412.

Sun CA, Chen HC, Lu CF, You SL, Mau YC, Ho MS, Lin SH, Chen CJ. 1999. Transmission of hepatitis C virus in Taiwan: prevalence and risk factors based on a nationwide survey. Journal of medical virology 59(3), 290-296.

ur Rehman L, Ullah I, Ali I, Khan IA, Iqbal A, Khan S, Khan SH, Zaman KU, ullah Khan N, Swati ZA. 2011. Active hepatitis C infection and HCV genotypes prevalent among the IDUs of Khyber Pakhtunkhwa. Virology journal 8(1), 1.

WHO. (2015). 14. Hepatitis B Fact sheet from http://www.who.int/mediacentre/factsheets/fs204/en/

Wright TL. 2006. Introduction to chronic hepatitis B infection. American journal of gastroenterology 101, S1.

Yousaf A, Mohammad A, Ishaque M, Yousaf M. 1996. Can we afford to operate on patients without HBs Ag screening. J Coll Phys Surg Pak 9, 98-100.

Yousfani S, Mumtaz F, Memon A, Memon MA, Sikandar R. 2006. Antenatal screening for hepatitis B and C virus carrier state at a university hospital. JLUMHS 5, 24-27.

Zein NN. 2000. Clinical significance of hepatitis C virus genotypes. Clinical microbiology reviews 13(2), 223-235.