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Two new antioxidant anthraquinones namely Obtusifolate C & D from Rumex obtusifolius

By: Abdul Khabir, Farman Ullah Khan, Zia ul Haq, AmirMiraj Hussain Shah, Malik Aman Ullah, Abdusubhan, Fawad Ali, Shafiullah Khan

Key Words: Rumex obtusifolius, Obtusifolate C, Obtusifolate D, DPPH radical scavenging activity

Int. J. Biosci. 10(5), 139-145, May 2017.

DOI: http://dx.doi.org/10.12692/ijb/10.5.139-145

Abstract

Rumex obtusifolius L. (Polygonaceae) is one of the most common wayside weeds and commonly known as broad-leaf dock. This plant is used for treatment of sores, tumors, blisters, burnsand cancer. It is also used as an antidote to nettle, depurative, astringent, tonic and laxative. Two new anthraquinones namely Ethyl 2-(18,18-dimethylbutanoyl)-1-methyl9,10-dioxo-5-(2-oxopropyl) anthraquinone-7-carboxylate (Obtusifolate C) and Ethyl 2-(16,16-dimethylbutanoyl) -4-methoxy, -1-methyl 9,10-dioxo, anthraquinone-7-carboxylate (Obtusifolate D) were isolated from Rumex Obtusifolius. The structures were elucidated by chemical and spectroscopic methods i.e. 1H and 13C NMR, UV, IR and mass spectrometry. Both the compounds showed significant antioxidant activities in the DPPH radical scavenging assay (RSA). The diverse medicinal importance of Rumex obtusifolius compels us to this work.

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Two new antioxidant anthraquinones namely Obtusifolate C & D from Rumex obtusifolius

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Abdul Khabir, Farman Ullah Khan, Zia ul Haq, AmirMiraj Hussain Shah, Malik Aman Ullah, Abdusubhan, Fawad Ali, Shafiullah Khan.
Two new antioxidant anthraquinones namely Obtusifolate C & D from Rumex obtusifolius.
Int. J. Biosci. 10(5), 139-145, May 2017.
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