International network for natural sciences – research journal
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Renal function impairment in insulin dependent and non-insulin dependent diabetic patients

By: Rasool Muhammad, Khakemin Khan, Inayat Ullah, Nazir Ahmad, Sohail Ahmad Jan, Bo-Xuan Gao, Shah Faisal, Mian Khizar Hayat, Wasim Sajjad, Tanweer Kumar

Key Words: Diabetic patients, Insulin dependent diabetic, Non-insulin dependent diabetic, Renal dysfunction.

Int. J. Biosci. 9(3), 89-98, September 2016.



Diabetes mellitus is one of the chronic metabolic disorder that cause serious renal problems. The present study was undertaken to investigate the effect of renal dysfunction in insulin dependent and non-insulin dependent diabetic patients. Samples of 100 individuals were collected i.e. 33 individuals from each insulin dependent and non-insulin dependent diabetic patients and 34 were control group. Blood samples from the individuals were collected for glucose estimation in sodium flurried tube while urine, creatinine and uric acid values were determined through lithium heparin coated tube. The weight was found significant in both groups as compared to control, while other parameters such as population, habits, nutrition and body mass index (gender, age, ethnic groups, location, marital status, occupation income/month, smoking, alcohol, drugs, dietary habits, dietary assessment, obesity, height) were non-significant (P>0.05). In case of disease effects, body effects, serum, urinary profile the parameters (duration, family history of disease, treatment, blood sugar, blood urea, blood creatinine, urinary protein, urinary sugar) were found highly significant (P<0.05) in both groups of diabetic patients, while the other parameters (diabetes, diabetes types, allergy, blood pressure (upper) blood pressure (lower), radial pulse, hypertension, heart disease, doctor visit, and uric acid) were non-significant between different groups. It is concluded that renal function was affected in both groups of diabetic patients based on data received from the above different parameters.


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