International network for natural sciences – research journal
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Phytochemical screening, evaluation of antioxidant and antimicrobial properties of Erythrophleum ivorense A. Chev (Leguminosae) and Megaphrynium macrostachyum Benth (Marantaceae), Medicinal plants from Gabon

By: Sima Obiang Cédric, Ondo Joseph-Privat, Obame Engonga Louis-Clément, Padzys Guy-Stéphane, Zongo Cheikna, BONGUI Jean-Bernard, Nsi Emvo Edouard, Traore Alfred

Key Words: Erythrophleum ivorense, Megaphrynium macrostachyum, antimicrobial and antioxidant activities.

Int. J. Biosci. 8(6), 43-53, June 2016.



Medicinal plants are used worldwide as an alternative and/or a complementary medicine, thus the valorization of the medicinal plants of our country and determination of their impact on health due to their abundance of substances with various pharmacological effects are our principal objective. The water, water-ethanol and ethanol extracts of Erythrophleum ivorense and Megaphrynium macrostachyum, were evaluated for antimicrobial and antioxidant activities. The powdered plants samples were analyzed for their phytochemical screening using standard laboratory methods. The total phenols, flavonoid and antioxidant activities were evaluated with methods of the Folin-Ciocalteu, aluminum chloride and Antioxidant Activity Index (AAI) assay, respectively. The antimicrobial activity was evaluated by analyses of diffusion and micro dilution. The phytochemical analysis highlights the presence of total polyphenols and the flavonoids in the extracts of Erythrophleum ivorense compared to the extracts of Megaphrynium macrostachyum. Water, water-ethanol and ethanol extracts of Erythropleum ivorense showed a strong antioxidant activity (AAIWE=1.58; AAIWEE = 2.87; AAIEE = 2.38). The extracts of Megaphrynium macrostachyum have antimicrobial and antioxidant activities weak, compared to the extracts of Erythrophleum ivorense, Vitamin C and BHA. The use of these plants in traditional medicine is justified and they constitute a source for other traditional investigations.


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