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Physiochemical extraction, spectroanalytical identification, antibacterial and docking studies of four new source phytochemicals from the bark of Millettia ovalifolia

By: Taj Ur Rahman, Muhammad Aurang Zeb, Sajjad Hussain, Wajiha Liaqat

Key Words: Millettia ovalifolia, Physiochemical extraction, Spectral analysis, Phytochemicals, Antibacterial, Docking.

Int. J. Biosci. 11(1), 222-231, July 2017.

DOI: http://dx.doi.org/10.12692/ijb/11.1.222-231

Certification: ijb 2017 0026

Abstract

The Spectroanalytical analysis and physiochemical extraction of bark of Millettia ovalifolia yielded phytochemicals, which included four new source compounds comprising of flavonoid characterized as 3,7-Dihydroxy-2-phenyl-4H-chromen-4-one, cinnamic acids, characterized as (E)-Ethyl 13-(3,4-dimethoxyphenyl) acrylate, (E)-Methyl 3-(3,4-dimethoxyphenyl) acrylate and N-Ethylacetamide. These isolated compounds were characterized by using advance modern Spectro analytical techniques such as UV, IR, 1D, 2D NMR and mass spectrometry. The isolated compounds were further studies for their antibacterial potency and docking studies.

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Physiochemical extraction, spectroanalytical identification, antibacterial and docking studies of four new source phytochemicals from the bark of Millettia ovalifolia

Ali SI. Flora of Pakistan: Shamim Printing Press: Karachi, 1977 100, 51-52.

Carron Ra, Maran JM, Montero L, Fernandozaigo L, Dominguez AA. 1987. Pl. Med. Phytother 21, 195-202.

Fuendjiep V, Nkengfack AE, Fomum ZT, Sondengam BL, Bodo B. 1998. Conrauinones C and D, two isoflavones from stem bark of Millettia conraui. Phytochemistry 47(1), pp.113-115.

Jakupovic J. 2003. New caffeic acid esters from Plazia daphnoides. Zeitschrift für Naturforschung C 58(1-2), pp.39-41.

Ito C, Itoigawa M, Tan HT, Tokuda H, Mou XY, Mukainaka T, Ishikawa T, Nishino H, Furukawa H. 2000. Anti-tumor-promoting effects of isoflavonoids on Epstein–Barr virus activation and two-stage mouse skin carcinogenesis. Cancer letters 152(2), pp.187-192.

Katsuhiko ONO, NAKANE H, Zeng-Mu MENG, Youki OSE, SAKAI Y, MIZUNO M, 1989. Differential inhibitory effects of various herb extracts on the activities of reverse transcriptase and various deoxyribonucleic acid (DNA) polymerases. Chemical and Pharmaceutical Bulletin 37(7), pp.1810-1812.

Ngamga D, Free SF, Tane P, Fomum ZT. 2007. Millaurine A, a new guanidine alkaloid from seeds of Millettia laurentii. Fitoterapia 78(3), pp.276-277.

Palazzino G, Rasoanaivo P, Federici E, Nicoletti M, Galeffi C. 2003. Prenylated isoflavonoids from Millettia pervilleana.  Phytochemistry 63(4), pp.471-474.

Shafaghat A, Salimi FARSHID. 2008. Extraction and determining of chemical structure of flavonoids in Tanacetum parthenium (L.) Schultz. Bip. from Iran. Journal of Sciences Islamic Azad University 18(68), pp.39-42.

Wolfrom ML, Benton FL, Gregory AS, Hess WW, Mahan JE, Morgan PW. 1939. Osage orange pigments. II. Isolation of a new pigment, pomiferin. Journal of the American Chemical Society 61(10), pp.2832-2836.

Yankep E, Mbafor JT, Fomum ZT, Steinbeck C, Messanga BB, Nyasse B, Budzikiewicz H, Lenz C, Schmickler H. 2001. Further isoflavonoid metabolites from Millettia griffoniana (Bail). Phytochemistry 56(4), pp.363-368.

Yenesew A, Derese S, Midiwo JO, Heydenreich M, Peter MG. 2003. Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti. Pest management science 59(10), pp.1159-1161.

Yenesew A, Derese S, Midiwo JO, Oketch-Rabah HA, Lisgarten J, Palmer R, Heydenreich M, Peter MG, Akala H, Wangui J, Liyala P. 2003. Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis. Phytochemistry 64(3), pp.773-779.

Taj Ur Rahman, Muhammad Aurang Zeb, Sajjad Hussain, Wajiha Liaqat.
Physiochemical extraction, spectroanalytical identification, antibacterial and docking studies of four new source phytochemicals from the bark of Millettia ovalifolia.
Int. J. Biosci. 11(1), 222-231, July 2017.
http://www.innspub.net/ijb/physiochemical-extraction-spectroanalytical-identification-antibacterial-docking-studies-four-new-source-phytochemicals-bark-millettia-ovalifolia/
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