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Occurence of aflatoxin M1 in Northern Africa: A short review

By: Redouane-Salah Sara, Messaï Ahmed, Abdeldjelil M-Cherif

Key Words: AFM1, Northern africa, Public health

Int. J. Biosci. 12(2), 64-75, February 2018.


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Moldy feed toxicosis was recognized as a serious livestock problem in the 1950’s. Mycotoxins are toxic metabolites synthesized by some naturally occurring fungi under suitable physical, chemical and biological factors. The Food and Agriculture Organization of the United Nations (FAO) estimated that approximately 25% of the cereals produced in the world are contaminated by mycotoxins. The aflatoxins constitute a group of fungal metabolites that have varied toxic properties. Among 17 aflatoxins isolated and identified, only 4 of them are well known and studied extensively ; B1, B2, G1 and G2. Aflatoxin B1 ingested by lactating animals is biotransformed in the liver to a monohydroxylated metabolite, aflatoxin M1 (AFM1), which is a toxic molecule excreted in the milk. Higher analytical costs of AFM1 are one of the reported reasons for unavailability of surveillance data in the majority of developing countries. In this review, occurrence of AFM1 in milk and milk products in northern Africa, as well as its metabolisme, properties and analytical methods are summarised.

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Occurence of aflatoxin M1 in Northern Africa: A short review

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Redouane-Salah Sara, Messaï Ahmed, Abdeldjelil M-Cherif.
Occurence of aflatoxin M1 in Northern Africa: A short review.
Int. J. Biosci. 12(2), 64-75, February 2018.
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