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The novel therapeutic implications of emerging biotechnologies in diagnostics and treatment of prostate cancer

By: Muhammad Naveed, Komal Imran, Ayesha Mushtaq, Sana Tehreem, Sami Ullah Khan

Key Words: Prostate cancer, Emerging biotechnologies, Newer molecular markers, miRNA, Prostate specific antigen (PSA)

Int. J. Biosci. 10(5), 22-42, May 2017.

DOI: http://dx.doi.org/10.12692/ijb/10.5.22-42

Abstract

The definitive goal of present study is to summarize the role of biotechnology in developing new therapeutic strategies for metastasized prostate cancer. Globally prostate cancer is considered as the second deadliest tumor of men due to limitations of standard therapies. Prostate cancer is highly prevalent in more developed countries such as America and Australia as compared to less developed countries. Traditional chemotherapeutic drugs and independent metastasized prostate cancer treatments poised the enthusiasm for advanced approaches such as immunotherapy, combined gene therapy and Nano biotechnology. These advanced initiatives promised better understandings of the genetic basis biochemical pathways of prostate cancer and make cancers therapies more personalized and predictive. Here we have provided a timely overview about current and near term applications of emerging biotechnologies as a perspective of future search regarding to in vitro diagnostics, in vivo diagnosis and in vivo therapeutics. This review outlines the importance of early prostate cancer diagnosis by tackling the problems of tumor microenvironment interactions with the hope of advancing new concepts in the era of treatment. Furthermore, study explained recent trends of prostate cancer incidence, mortality and survival rate among developed and Asian countries that would urge scientists for the development of newer molecular markers and imaging technologies for its management.

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The novel therapeutic implications of emerging biotechnologies in diagnostics and treatment of prostate cancer

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Muhammad Naveed, Komal Imran, Ayesha Mushtaq, Sana Tehreem, Sami Ullah Khan.
The novel therapeutic implications of emerging biotechnologies in diagnostics and treatment of prostate cancer.
Int. J. Biosci. 10(5), 22-42, May 2017.
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