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Level of serum heavy metal concentration in pregnant and non-pregnant women of district Sargodha: A comparative study

By: Faiza Zubair, Naila Amjad, Ammara Nawaz, Shafaat Yar Khan, Muhammad Arshad, Noor Nasir Khattak, Muhammad Saleem Khan

Key Words: Heavy metals, Pregnant females, Risk factor

Int. J. Biosci. 10(3), 350-356, March 2017.

DOI: http://dx.doi.org/10.12692/ijb/10.3.350-356

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Abstract

In present study, level of some heavy metals was evaluated among pregnant females living in industrial areas and compared with non-pregnant females in University of Sargodha. Blood samples were collected from females of different age group. The samples were processed through wet acid digestion and flame Atomic Absorption Spectroscopy was used for comparison. The mean values of blood Pb (104.4±78.1ppm), Zn (51.9±61ppm), Cd (31.2±19.9ppm) and Cr (10.5±10.7ppm) was significantly higher in pregnant females as compared to non-pregnant females. The present study concludes that increased blood level of Pb, Cd, Cr and decrease level of Cu may be a risk factor for pregnant females.

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Level of serum heavy metal concentration in pregnant and non-pregnant women of district Sargodha: A comparative study

Ajose A, Fasubaa B, Anetor J, Adelekan D, Makinde N. 2001. Serum zinc and copper concentrations in Nigerian women with normal pregnancy. The Nigerian postgraduate medical journal 8(4), 161-164.

Al-Rashid RA, Spangler J. 1971. Neonatal copper deficiency. New England Journal of Medicine 285(15), 841-843.

http://dx.doi.org/10.1056/nejm1 97110072851506.

Álvarez SI, Castañón SG, Ruata MLC, Aragüés EF, Terraz PB, Irazabal YG, González EG, Rodríguez BG. 2007. Updating of normal levels of copper, zinc and selenium in serum of pregnant women. Journal of trace elements in medicine and biology 21, 49-52.

http://dx.doi.org/10.1016/j. jtemb.2007.09.023.

Anderson RA, Bryden NA, Polansky MM, Gautschi K. 1996. Dietary chromium effects on tissue chromium concentrations and chromium absorption in rats. The Journal of Trace Elements in Experimental Medicine 9(1), 11-25.

http://dx.doi.org/10.1002/(sici)1520-670x(199607)9:1<11::aid-jtra2>3.3.co;2-3.

Anetor J, Babalola O, Adeniyi F, Akingbola T. 2002. Observations on the haematopoietic systems in tropical lead poisoning. Nigerian Journal of Physiological Sciences. 2002 17(1-2), 9-15.

Asghar MS, Quershi NA, Jabeen F, Shakeel M, Khan MS. 2016. Genotoxicity and oxidative stress analysis in the Catla catla treated with ZnO NPs. Journal of Biodiversity and Environmental Sciences 8(4), 91-104.

Asghar MS, Qureshi NA, Jabeen F, Khan MS, Shakeel M, Noureen A. 2015. Toxicity of zinc nanoparticles in fish: a critical review. Journal of Biodiversity and Environmental Sciences 7(1), 431-439.

Awasthi S, Awasthi R, Pande VK, Srivastav R, Frumkin H. 1996. Blood lead in pregnant women in the urban slums of Lucknow, India. Occupational and environmental medicine 53(12), 836-840.

Bahl L, Chaudhuri L, Pathak R. 1994. Study of serum zinc in neonates and their mothers in Shimla hills (Himachal Pradesh). Indian journal of pediatrics 61(5), 571-575.

http://dx.doi.org/10.1136/oem.53.12.836.

Baranowska I. 1995. Lead and cadmium in human placentas and maternal and neonatal blood (in a heavily polluted area) measured by graphite furnace atomic absorption spectrometry. Occupational and environmental medicine 52(4), 229-232.

http://dx. doi.org/10.1136/oem.52.4.229.

Chernoff R. 2005. Micronutrient requirements in older women. The American journal of clinical nutrition 81(5), 1240S-1245S.

Colagar AH, Marzony ET, Chaichi MJ. 2009. Zinc levels in seminal plasma are associated with sperm quality in fertile and infertile men. Nutrition Research 29(2), 82-88.

http://dx.doi.org/10.1016/j. nutres.2008.11.007.

Colborn T, Dumanoski D, Myers JP. 1996. Our Stolen Future: Are We Threatening Our Fertility, Intelligence and Survival?–a Scientific Detective Story. Choice Reviews Online 33(11), 33-6336. http://dx.doi.org/10.5860/choice.33-6336.

Corporation P-E. 1964. Analytical methods for atomic absorption spectrophotometry.

Dayan A, Paine A. 2001. Mechanisms of chromium toxicity, carcinogenicity and allergenicity: review of the literature from 1985 to 2000. Human & experimental toxicology 20(9), 439-451. http://dx.doi.org/10.1191/096032701682693062.

Dreosti I, McMichael AJ, Gibson G, Buckley R, Hartshorhe J, Colley D. 1982. Fetal and maternal serum copper and zinc levels in human pregnancy. Nutrition research 2(5), 591-602. http://dx.doi.org/10.1016/s0271-5317(82)80071-7.

Finkelman J. 1996. Phasing out leaded gasoline will not end lead poisoning in developing countries. Environmental health perspectives 104(1), 10. http://dx.doi.org/10.2307/3432745

Gerhard I, Waibel S, Daniel V, Runnebaum B. 1998. Impact of heavy metals on hormonal and immunological factors in women with repeated miscarriages. Human reproduction update 4(3), 301-309.

http://dx.doi.org/10.1093/humupd/4.3.301.

Glanze WD, Anderson K, Anderson LE. 1986. Mosby’s medical & nursing dictionary: CV Mosby. St. Louis, MO: Mosby.

Hamid A, Khan MU, Yaqoob J, Umar A, Rehman A, Javed S, Sohail A, Anwar A, Khan MS, Ali A. 2016. Assessment of mercury load in river Ravi, urban sewage streams of Lahore Pakistan and its impact on the oxidative stress of exposed fish Journal of Biodiversity and Environmental Sciences 8(4), 63-72.

Khan MS, Jabeen F, Qureshi NA, Asghar MS, Shakeel M, Noureen A. 2015. Toxicity of silver nanoparticles in fish: a critical review. Journal of Biodiversity and Environmental Sciences 6(5), 211-227.

Khan MS, Qureshi NA, Jabeen F, Asghar MS, Shakeel M, Fakhar -e -Alam M. 2016. Eco-Friendly Synthesis of Silver Nanoparticles Through Economical Methods and Assessment of Toxicity Through Oxidative Stress Analysis in the Labeo Rohita. Biological Trace Element Research 1-13. http://dx.doi.org/10.1007/s12011-016-0838-5.

McMichael A, Dreosti I, Gibson G, Hartshorne J, Buckley R, Colley D. 1982. A prospective study of serial maternal serum zinc levels and pregnancy outcome. Early Human Development 7(1), 59-69. http://dx.doi.org/10.1016/0378-3782(82)90008-1.

Meram I, Bozkurt AI, Ahi S, Ozgur S. 2003. Plasma copper and zinc levels in pregnant women in Gaziantep, Turkey. Saudi medical journal 24(10), 1121-1125.

Miranda ML, Edwards SE, Swamy GK, Paul CJ, Neelon B. 2010. Blood lead levels among pregnant women: historical versus contemporaneous exposures. International journal of environmental research and public health 7(4), 1508-1519. http://dx.doi.org/10.3390/ijerph7041508

Nkolika IC, Benedict OCO. 2009. Elevated cadmium levels in blood of the urban population in Enugu State Nigeria. World Applied Sciences Journal 7(10), 1255-1262.

Olaifa F, Ayodele I. 2004. Presence of hydrocarbons and heavy metals in some fish species in the Cross River, Nigeria. African Journal of Livestock Extension 3, 90-95.

Pathak P, Kapil U. 2004. Role of trace elements zinc, copper and magnesium during pregnancy and its outcome. The Indian Journal of Pediatrics 71(11), 1003-1005.

http://dx.doi.org/10.1007/bf02828116.

Pathak P, Kapoor SK, Kapil U, Joshi YK, Dwivedi SN. 2003. Copper nutriture amongst pregnant women in a rural area of India. Eastern Journal of Medicine 8, 15-17.

Prasad AS. 2008. Zinc in human health: effect of zinc on immune cells. Molecular Medicine-Cambridge Ma Then New York 14(5/6), 353.

Salpietro CD, Gangemi S, Minciullo PL, Briuglia S, Merlino MV, Stelitano A, Cristani M, Trombetta D, Saija A. 2002. Cadmium concentration in maternal and cord blood and infant birth weight: a study on healthy non-smoking women. Journal of perinatal medicine 30(5), 395-399. http://dx.doi.org/10.1515/jpm.2002.061.

Stern BR, Solioz M, Krewski D, Aggett P, Aw T-C, Baker S, Crump K, Dourson M, Haber L, Hertzberg R. 2007. Copper and human health: biochemistry, genetics, and strategies for modeling dose-response relationships. Journal of Toxicology and Environmental Health, Part B 10(3), 157-222. http://dx.doi.org/10.1080/10937400600755911.

Terrin G, Berni Canani R, Di Chiara M, Pietravalle A, Aleandri V, Conte F, De Curtis M. 2015. Zinc in early life: a key element in the fetus and preterm neonate. Nutrients 7(12), 10427-10446. http://dx.doi.org/10.3390/nu7125542.

Umar A, Sohail A, Javed S, Yaqoob J, Hamid A, Arshad T, Khalid M, Khan MU, Khan MS. 2016. Biosorption of some toxic metals by pine nut shell from contaminated waste water. Journal of Biodiversity and Environmental Sciences 9(1), 465-473.

Wätjen W, Haase H, Biagioli M, Beyersmann D. 2002. Induction of apoptosis in mammalian cells by cadmium and zinc. Environmental health perspectives110 (Suppl 5), 865.

http://dx.doi.org/ 10.1289/ehp.02110s5865.

Faiza Zubair, Naila Amjad, Ammara Nawaz, Shafaat Yar Khan, Muhammad Arshad, Noor Nasir Khattak, Muhammad Saleem Khan.
Level of serum heavy metal concentration in pregnant and non-pregnant women of district Sargodha: A comparative study.
Int. J. Biosci. 10(3), 350-356, March 2017.
http://www.innspub.net/ijb/level-serum-heavy-metal-concentration-pregnant-non-pregnant-women-district-sargodha-comparative-study/
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