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Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?

By: Anubrata Ghosal

Key Words: PNA, Drug resistance bacteria, Antibiotics

Int. J. Biosci. 10(1), 408-410, January 2017.

DOI: http://dx.doi.org/10.12692/ijb/10.1.408-410

Abstract

The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to
patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics.
Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90’s as antibacterial agents in an intention to create a new class of bacterial specific antibiotic. Followed by several studies have demonstrated that antibacterial PNA oligomers are effective in a verity of pathogenic bacterial strains. Development of PNA-based drugs (PNA antibiotics) will help us to combat infections of drug resistant bacterial strains.

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Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?

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Anubrata Ghosal.
Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?.
Int. J. Biosci. 10(1), 408-410, January 2017.
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