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Histopathology of liver and kidneys for the assessment of genotoxicity in Indian major carps treated with domestic waste and industrial effluents of Chakbandi drain water

By: Muhammad Arshad Rana, Tayyaba Sultana, Salma Sultana, Bilal Hussain

Key Words: Effluent, Composite, Toxicity, Histopathological, Biomarker, Pollution

Int. J. Biosci. 11(6), 178-186, December 2017.

DOI: http://dx.doi.org/10.12692/ijb/11.6.178-186

Certification: ijb 2017 0172 [Generate Certificate]

Abstract

This project was planned to study the exposure effects of domestic waste and industrial effluents on water quality parameters and fish under laboratory conditions. Faisalabad the so called “Manchester” of Pakistan has plastic, leather, textile, dying, printing, finishing, seizing industries, sugar mills and a large number of factories that release the variety of industrial discharges and municipal wastes into River Chenab through Chakbandi drain. In this study, Chakbandi drain’s water was collected from the selected sites in the month of April, May and June, 2016 and applied to fingerling’s of three Indian major carps i.e. Catla catla, Labeo rohita and Cirrhinus mrigala under laboratory conditions in glass aquaria. After determining the LC50, the sub-lethal dilutions i.e. 20%, 25%, 30%, 35% and 40% of drain water were tested for three month’s acute toxicity trial. After three months, fish tissues i.e. liver and kidneys were taken by dissecting the control and experimental fishes for histopathological studies. Histopathological analysis of control fish revealed the normal structures whereas treated fish showed different abnormalities with respect to liver and kidney tissues. Conclusively, histopathological biomarkers approach was found to be reliable for the assessment of environmental pollution. Moreover, findings of this study are helpful for the evaluation of pollution levels reaching in aquatic fauna particularly fish and indirectly to human populations.

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Histopathology of liver and kidneys for the assessment of genotoxicity in Indian major carps treated with domestic waste and industrial effluents of Chakbandi drain water

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Muhammad Arshad Rana, Tayyaba Sultana, Salma Sultana, Bilal Hussain.
Histopathology of liver and kidneys for the assessment of genotoxicity in Indian major carps treated with domestic waste and industrial effluents of Chakbandi drain water.
Int. J. Biosci. 11(6), 178-186, December 2017.
http://www.innspub.net/ijb/histopathology-liver-kidneys-assessment-genotoxicity-indian-major-carps-treated-domestic-waste-industrial-effluents-chakbandi-drain-water/
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