Hematological malignancies in Cameroonian women with cancer attending a health facility: High prevalence and implications for follow up
By: Idriss Lemouchele Ntatou, Martin Luther Mogtomo Koanga, Cecile Okalla Ebongue, Esther Dina Bell, Nkeumacha Ida Patrick, Loick Pradel Foko Kojom, Elisée Enyegue Embolo, Martin Biwole Essomba, Eliane Okoubalimba Assokom, Anne Marie Maïsson, Annie Rosalie Ngane Ngono, Albert SoneMoelle
Key Words: Hematological disorders, Cervical cancer, Breast cancer, Anti-cancer treatment, Douala.
Int. J. Biosci. 9(1), 72-82, July 2016.
This study aimed at determining the prevalence of hematological malignancies in cancer patients and discussing about implications for follow-up. A five-month hospital-based cross sectional study was carried out in 2015 in the town of Douala, Cameroon. Personal data were documented and 4 mL of venous blood was collected for full blood count. A total of 172 women were enrolled and divided into three groups: 74 in the cervical cancer group (CCG), 69 in the breast cancer group (BCG) and 29 in the control group (CG). Radiotherapy associated with chemotherapy was the most used therapeutic option (> 50.0 %). The prevalence of hematological disorders was 86.5 %, 75.4 % and 51.7 % in CCG, BCG and CG respectively (χ2 = 13.909; p-value < 0.0001). Anemia was the most observed disorder and accounted for more than 40 % of all disorders observed in the three groups. Cancer and its therapy have negatively affected each of the blood parameters analyzed (p-value < 0.05).Our findings suggest the need for cautious and adjusted follow-up of Cameroonian cancer patients through surrogate markers such as blood parameters in order to enhance their life expectancy.