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Antimalarial potential of leaves crude extract of Callistemon lanceolatus D.C.

By: Muhammad Binyamin Khan, Muhammad Afzal, Yasir Ihtesham, Muhammad Sadiq, Ejaz Ahmad Khan, Muhammad Fiaz, BurhanUd Din, Muhammad Idrees Khan, Muhammad Safdar Baloch, Najeeb Ullah

Key Words: Callistemon lanceolatus D.C., Crude extracts, Anti-malarial activity.

Int. J. Biosci. 11(5), 11-20, November 2017.

DOI: http://dx.doi.org/10.12692/ijb/11.5.11-20

Certification: ijb 2017 0124 [Generate Certificate]

Abstract

Plants have been used from ancient times for various purposes like food, shelter and also as a medicine to treat various diseases. The current study was based on an investigation of cheap and herbal drugs against malarial parasite. For the study, chloroform fractions of Callistemon lanceolatus of dose concentration 200µl/ml were applied against the malaria parasite. The blood samples (n=67) from male and female of various ages were collected from district Bannu. It was identified that 200µl/ml of chloroform fraction application demonstrated 54.58% inhibition (males=54.70%) of the malarial parasite. The Nivaquine (40 µg/ml) used as positive control exhibited 100% inhibition of malaria parasite. Additionally, distilled water used as negative control (200µl/ml) showed neutral effect. Conclusively, it is found that the chloroform fractions (200µl/ml) of Callistemon lanceolatus are effective against malaria disease and may the varied dose concentration be more profound against the disease.

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Antimalarial potential of leaves crude extract of Callistemon lanceolatus D.C.

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Muhammad Binyamin Khan, Muhammad Afzal, Yasir Ihtesham, Muhammad Sadiq, Ejaz Ahmad Khan, Muhammad Fiaz, BurhanUd Din, Muhammad Idrees Khan, Muhammad Safdar Baloch, Najeeb Ullah.
Antimalarial potential of leaves crude extract of Callistemon lanceolatus D.C..
Int. J. Biosci. 11(5), 11-20, November 2017.
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