Analytical study of bacterial vaginal infections including antimicrobial assessment in Asser Region, Saudi Arabia
By: AA Osman, NM Abdalla, HE Mubasher, MN Mohamed
Key Words: High vaginal swab, Vaginitis, Antibacterial resistance
Int. J. Biosci. 9(2), 126-136, August 2016.
This study aimed to evaluate antimicrobial susceptibility of vaginal bacterial infections isolates in Asser region, Saudi Arabia. A cross section hospital based study was conducted. Out of 150 sample of high vaginal swab collected through three month, 15 women had bacterial vaginal infections. Each collection swab was initially inoculated into Muller Hinton agar then impregnated antibiotics filter paper was immersed after incubation 48 hrs, the antibiotics sensitivity was determined by measuring the minimum inhibitory concentration (MIC) of each antibiotic, for most common prescribed antibiotics (20drugs). The final result as follows: For E. coli, a drug which is of absolute resistance (100%) was Ampcillin and these with 100% sensitive were Nitrofurantoin and Amikacine. Sensitivity of other drugs range from 50 to75% resistance. Regarding Enterobacter, 100% resistance found in 3 drugs, Ampcillin, Augmentin and Cotrimaxcillin. While 100% sensitivity present in 5 drugs which were Nitrofurantoin, Imipenem, Gentamycin, Ciprofloxacin and Amikacin. In Klebsiella pneumoni drugs with 100% resistance were Cephalosporin, Ceftazidime, Ampcillin and Augmentin. Almost all other drugs were sensitive. The fourth organism is Staphylococcus aureus, 100% resistance found in Ampcillin Augmentin, Pencillin, Cifoxtine. 100% sensitivity in Cotrimxacillin, Tetracycline, Gentamycin and vancomycin. Last organism was Streptococcus agalactica, 100% resistance to Ampcillin, Augmentin,Tetracycline, Pencillin, erythromycin and Cifoxatine. Other drugs were 50% sensitive and 50% resistance. As conclusion, treatment of bacterial vaginosis is getting more difficult due to emerge of antibiotics resistance.